In vivo antipyretic activity of Scutia myrtina acute oral toxicity study

Pyrexia or Fever is defined as an elevation of body temperature. It a response due to tissue damage, inflammation, malignancy graft rejection. Cytokines, interleukin, interferon and Tumor Necrosis Factor α (TNF- α) are formed in large amount under this condition, which increase PGE2 turn triggers hypothalamus elevate The present investigation it may be concluded that the hydroalcoholic extract leaves Scutia myrtina has antipyretic activity.it tested by vivo method using rat .In study contain fever reducing activity.